Science - Read it!
Variable susceptibility of intestinal organoid-derived monolayers to SARS-CoV-2 infection
Exciting collaboration with the Cadwell Lab at NYU addressing how different gut organoids get infected with SARS-CoV-2.
Emerging Chikungunya Virus Variants at the E1-E1 Interglycoprotein Spike Interface Impact Virus Attachment and Inflammation
Margarita's main thesis work describing how emerging CHIKV variants do wild things!
Structurally Conserved Domains between Flavivirus and Alphavirus Fusion Glycoproteins Contribute to Replication and Infectious-Virion Production
Fun collaboration with the Lazear Lab at UNC Chapel Hill defining how the Zika virus envelope functions.
Atovaquone and Berberine Chloride Reduce SARS-CoV-2 Replication In Vitro
The team links up with Margaret Kielian's Lab at Albert Einstein to test antivirals against SARS-CoV-2.
Margarita reviews what makes alphaviruses so interesting.
Antibody isotype diversity against SARS-CoV-2 is associated with differential serum neutralization capacities
Exciting collaboration throughout NYU investigating the antibody response to SARS-CoV-2.
Mapping the Evolutionary Landscape of Zika virus Infection in Immunocompromised mice.
Awesome collaboration with the Ghedin Lab (https://wp.nyu.edu/ghedinlab/) and Cadwell Lab (http://cadwelllab.med.nyu.edu/) studying how Zika virus evolves
Distinct New York City Aedes albopictus Mosquito Populations Display Differences in Salivary Gland Protein D7 Diversity and Chikungunya Virus Replication
Maryska characterizes antiviral factors and CHIKV replication and evolution in New York City mosquitoes!
Evolution-driven attenuation of alphaviruses highlights key glycoprotein determinants regulating viral infectivity and dissemination
First Stapleford Lab CHIKV dissemination paper! Gaby, Bruno, and Margarita identify a network of molecular interactions that modulate CHIKV infectivity and dissemination.
Atovaquone Inhibits Arbovirus Replication through the Depletion of Intracellular Nucleotides.
First paper from the Stapleford Lab! Angelica Kottkamp defines the antiviral mechanism of the antiparasitic drug atovaquone.